Does Diet matter when performing animal imaging studies?

By Matthew Ricci, Ph.D..

If your study involves in vivo imaging using fluorescence technologies, it's very important that the 'background' or 'noise' signal be as low as possible. Unfortunately, many commonly used grain-based chow diets contain chlorophyll, which fluoresces at 680 nm and can therefore interfere with the detection of fluorophores. The result is that the GI tract of the animal will fluoresce and your signal of interest may be hard or impossible to quantify.

Read more

Inside a Lab Mouse's High-Fat Diet

By Mark D'Antonio.

Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise. One of those experts is our own Matthew Ricci, Ph. D.- VP/Science Director. The article appears online in the Scientist.