Blog: Expression of SARS-CoV-2 entry proteins ACE2 and TMPRSS2 in rodents is affected by Obesity and Diabetes

By Dushyant Kshatriya, Ph.D. .

The COVID-19 pandemic has caused millions of deaths worldwide and caused significant impact on the global economy. The risk of severe coronavirus disease 2019 (COVID-19) is higher in people with diabetes and obesity. The exact mechanism by which obesity and diabetes contribute to the pathophysiology of COVID-19 is unknown and one of the key player is believed to be related to the renin-angiotensin system (RAS).

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