Is It Time to Revise the AIN-93 Rodent Diet Formulas?

By Michael A. Pellizzon, Ph.D..

This important question will be addressed at a special session during NUTRITION 2021 LIVE ONLINE, June 9, 2021 from 2:00 – 3:30 PM EDT. Michael A. Pellizzon, PhD from Research Diets, Inc. is presenting.

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Hematopoietic stem cell maintenance requires branched chain amino-acids.

By Sridhar Radhakrishnan, Ph.D..

The ease of modifying purified diets, with amino acids as the protein source, allowed to make such formulations that could be used in lieu of complex procedures like myeloablation and could make the process of HSCs engraftment an easy procedure in rodents.

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Research Diets’ own Dr. Laura Griffin publishes paper showing that use of genetically diverse mouse strains may help translatability to humans

By Mark D'Antonio.

Despite evidence suggesting that natural products protect against obesity and metabolic syndrome in cell culture and animal models, results oftentimes do not translate in human clinical trials. One possible explanation for this finding is the...

mark

Publication: A Translational Mouse Model for NASH

By Sridhar Radhakrishnan, Ph.D..

An interesting publication using NASH diets ...

A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Anita M. van den Hoek 1,*, Lars Verschuren 2, Nicole Worms 1, Anita van...

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Targeted Nutrient Modifications in Purified Diets Differentially Affect Nonalcoholic Fatty Liver Disease and Metabolic Disease Development in Rodent Models

By Sridhar Radhakrishnan, Ph.D..

Sridhar Radhakrishnan, Jia-Yu Ke, Michael A Pellizzon
Current Developments in Nutrition, Volume 4, Issue 6, June 2020

ABSTRACT
Nonalcoholic fatty liver disease (NAFLD) is a complex spectrum of disorders ranging from simple benign steatosis to more...

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Mycotoxins and Endotoxin Content Vary Between Different Batches of Grain-Based Diets

By Sridhar Radhakrishnan, Ph.D..

by Sridhar Radhakrishnan, Ph.D. and Michael Pellizzon, Ph.D. - Research Diets, Inc.

We measured endotoxins in at least 3 separate lots of 5 different GB diets as well as the purified diets D11112201 (15 kcal% fat), D12492 (60 kcal% fat) and ...

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Diet is important in changing the microbiome

By Mark D'Antonio.

Here’s a link to a recent Time magazine article on the microbiome:

http://time.com/5360407/microbiome-diet-gut-health/

It references work by our customer, Krzysztof Czaja.

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Research Diets scientist quoted in Nature article

By Mark D'Antonio.

In last month’s Nature Medicine, Dan Engber wrote a nice article about the efforts to standardize high-fat diets to make rodents obese, and the pitfalls of a ‘one diet fits all’ approach. He also points out the lack of attention that is generally...

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Fiber Is Good for You. Now Scientists May Know Why.

By Mark D'Antonio.

Research Diets formulated diets for the Gewirtz lab referenced in this article http://www.nytimes.com/2018/01/01/science/food-fiber-microbiome-inflammation.html

mark

Are you choosing the right diets to make your mice fat?

By Sridhar Radhakrishnan, Ph.D..

A recently published review article summarizes multiple studies in this area and has revealed some startling observations.

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Vijay Indukuri, Ph.D.

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Sridhar Radhakrishnan, Ph.D.

Project Manager and Scientist