Research Diets’ own Dr. Laura Griffin publishes paper showing that use of genetically diverse mouse strains may help translatability to humans

By Mark D'Antonio.

Despite evidence suggesting that natural products protect against obesity and metabolic syndrome in cell culture and animal models, results oftentimes do not translate in human clinical trials. One possible explanation for this finding is the...

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Blog: A Translational Mouse Model for NASH

By Sridhar Radhakrishnan, Ph.D..

An interesting publication using NASH diets ...

A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Anita M. van den Hoek 1,*, Lars Verschuren 2, Nicole Worms 1, Anita van...

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Publication: Targeted Nutrient Modifications in Purified Diets Differentially Affect Nonalcoholic Fatty Liver Disease and Metabolic Disease Development in Rodent Models

By Sridhar Radhakrishnan, Ph.D..

Sridhar Radhakrishnan, Jia-Yu Ke, Michael A Pellizzon
Current Developments in Nutrition, Volume 4, Issue 6, June 2020

ABSTRACT
Nonalcoholic fatty liver disease (NAFLD) is a complex spectrum of disorders ranging from simple benign steatosis to more...

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Publication: Choice of Laboratory Rodent Diet May Confound Data Interpretation and Reproducibility

By Michael A. Pellizzon, Ph.D..

Michael A Pellizzon and Matthew R Ricci
Research Diets, Inc, New Brunswick, NJ, USA

ABSTRACT
The reproducibility of experimental data is challenged by many factors in both clinical and preclinical research. In preclinical studies, several factors...

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Mycotoxins and Endotoxin Content Vary Between Different Batches of Grain-Based Diets

By Sridhar Radhakrishnan, Ph.D..

by Sridhar Radhakrishnan, Ph.D. and Michael Pellizzon, Ph.D. - Research Diets, Inc.

We measured endotoxins in at least 3 separate lots of 5 different GB diets as well as the purified diets D11112201 (15 kcal% fat), D12492 (60 kcal% fat) and ...

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Diet is important in changing the microbiome

By Mark D'Antonio.

Here’s a link to a recent Time magazine article on the microbiome:

http://time.com/5360407/microbiome-diet-gut-health/

It references work by our customer, Krzysztof Czaja.

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The biggest study that's been done in mouse nutrition in 50 years by John Speakman, PhD

By Mark D'Antonio.

In a landmark paper published in Cell Metabolism in September of 2018,  John Speakman, (with joint appointments at University of Aberdeen and the Chinese Academy of Sciences) et al., studied the effects of 29 different diets that varied in...

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Dr. Pellizzon and Dr. Ricci published in Current Protocols in Toxicology

By Mark D'Antonio.

Our invited paper entitled “Effects of Rodent Diet Choice and Fiber Type on Data Interpretation of Gut Microbiome and Metabolic Disease Research” is available online as an epub and was made open access by Current Protocols in Toxicology.

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Research Diets scientist quoted in Nature article

By Mark D'Antonio.

In last month’s Nature Medicine, Dan Engber wrote a nice article about the efforts to standardize high-fat diets to make rodents obese, and the pitfalls of a ‘one diet fits all’ approach. He also points out the lack of attention that is generally...

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Fiber Is Good for You. Now Scientists May Know Why.

By Mark D'Antonio.

Research Diets formulated diets for the Gewirtz lab referenced in this article http://www.nytimes.com/2018/01/01/science/food-fiber-microbiome-inflammation.html

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