Our invited paper entitled “Effects of Rodent Diet Choice and Fiber Type on Data Interpretation of Gut Microbiome and Metabolic Disease Research” is available online as an epub and was made open access by Current Protocols in Toxicology.
In last month’s Nature Medicine, Dan Engber wrote a nice article about the efforts to standardize high-fat diets to make rodents obese, and the pitfalls of a ‘one diet fits all’ approach. He also points out the lack of attention that is generally...
The common use of improper control diets in diet-induced metabolic disease research confounds data interpretation: the fiber factor
Diets used to induce metabolic disease are generally high in fat and refined carbohydrates and importantly, are usually made with refined, purified ingredients. However, researchers will often use a low fat grain-based (GB) diet containing...
Are you familiar with the difference between a grain based chow and a purified ingredient diet? RDI's Senior Scientist Dr.Michael Pellizzon talks about differences between these two types of diets and how they can influence the intestinal health...
If your study involves in vivo imaging using fluorescence technologies, it's very important that the 'background' or 'noise' signal be as low as possible. Unfortunately, many commonly used grain-based chow diets contain chlorophyll, which fluoresces at 680 nm and can therefore interfere with the detection of fluorophores. The result is that the GI tract of the animal will fluoresce and your signal of interest may be hard or impossible to quantify.Read more
Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise. One of those experts is our own Matthew Ricci, Ph. D.- VP/Science Director. The article appears online in the Scientist.
How important is a good control diet? Can't you just use chow as a control? (Short answer: No!)
Proper control diets are critical to valid data interpretation.
Click here to find out more!
Understandably, many customers are concerned about whether our production process involves any extreme temperatures or pressure. This is especially true when we are incorporating a sensitive compound. The answer is, no, diets are not exposed to...
- Dr. Pellizzon and Dr. Ricci published in Current Protocols in Toxicology
- Research Diets scientist quoted in Nature article
- Fiber Is Good for You. Now Scientists May Know Why.
- The common use of improper control diets in diet-induced metabolic disease research confounds data interpretation: the fiber factor
- Are you choosing the right diets to make your mice fat?
- Intestinal Health: Are you choosing the right type of diet for your lab animals?
- Does Diet matter when performing animal imaging studies?
- Inside a Lab Mouse's High-Fat Diet
- Are control diets important?
- Diets are not exposed to extreme temperatures during production