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Diets used to induce metabolic disease are generally high in fat and refined carbohydrates and importantly, are usually made with refined, purified ingredients. However, researchers will often use a low fat grain-based (GB) diet containing...

A recently published review article summarizes multiple studies in this area and has revealed some startling observations.

Are you familiar with the difference between a grain based chow and a purified ingredient diet? RDI's Senior Scientist Dr.Michael Pellizzon talks about differences between these two types of diets and how they can influence the intestinal health...

If your study involves in vivo imaging using fluorescence technologies, it's very important that the 'background' or 'noise' signal be as low as possible. Unfortunately, many commonly used grain-based chow diets contain chlorophyll, which fluoresces at 680 nm and can therefore interfere with the detection of fluorophores. The result is that the GI tract of the animal will fluoresce and your signal of interest may be hard or impossible to quantify.

Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise. One of those experts is our own Matthew Ricci, Ph. D.- VP/Science Director. The article appears online in the Scientist.

How important is a good control diet? Can't you just use chow as a control? (Short answer: No!)

Proper control diets are critical to valid data interpretation.

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Understandably, many customers are concerned about whether our production process involves any extreme temperatures or pressure. This is especially true when we are incorporating a sensitive compound. The answer is, no, diets are not exposed to...

How often do you change the diet in your animal's cages?

In 2008, Kozul-Horvath and Hamilton found that mice fed a grain-based chow (Purina 5001) had no changes in gene expression when exposed to arsenic while they were dramatic when fed purified diet AIN-76A (Click here for pdf). They found out that...